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产品说明 尿酸是一种嘌呤代谢的最终产物，对一名健康者来说，尿酸常被肾脏从血液中滤出并随尿液排出体外。由于很多肾脏疾病都会影响到血液中的尿酸含量，因此检测尿酸含量一直是诊断肾脏疾病的重要手段。当血液中的尿酸含量上升到一定程度时，容易在关节周围沉积生成痛风石（即尿酸盐结晶），从而引起痛风。此外，尿酸含量过高也可能与尿毒症、肺炎或有关。在科研和药物研发中，方便、直接、自动化的尿酸浓度检测手段是理想的。本公司研制的尿酸检测试剂盒可直接用于血清检测，免除了预处理过程。测试方法是利用显色试剂在尿酸存在的情况下反应生产蓝色络合物的特性，在波长为590nm下检测，其颜色深浅程度与血清中尿酸的含量对应成比例。并且通过配方的改良，充分减小了未处理的样品中其他杂质的干扰。
产品特点 测量敏感、准确：采用5μL样本，在96孔板中测试，尿酸的线性测试范围在0.22-30 mg/dL (13-2380μM)。简单、高通量：整个测试过程只需加入试剂并静置30分钟。利用96孔板的高通量检测手段，每天可以测试上千份样本。试剂稳定性高和多功能性：产品经过配方的改良，极大的提高了试剂和测试信号的稳定性，测试可采用比色皿或96孔板。受样本干扰小：样本无需预处理，可以直接测试血清样本。
产品用途 1．直接检测血清、血浆、尿液和其他生物样本中的尿酸含量。2．适用于新药开发和药理学研究，检测药物对尿酸代谢的影响。
储藏条件 可在室温下运输。试剂在4℃环境下保存，空白对照和标准品需在-20℃下保存。
DEscriptION Uric acid is the waste product produced from the degradation of purines. In healthy human, uric acid is filtered and removed from the blood by the kidneys and excreted into urine. Because a number of kidney diseases are known to affect uric acid levels, uric acid determination is thus important and useful in diagnosing and evaluating kidney diseases. For example, when uric acid is present in the blood at abnormally high levels, it tends to crystallize in body joints, resulting in gout, a very painful inflammatory condition. Increased levels of uric acid are also known to be associated with uremia, leukemia and pneumonia. Simple, direct and automation-ready procedures for measuring uric acid concentration in blood are becoming popular in Research and Drug Discovery. our uric acid assay kit is designed to measure uric acid directly in serum without any pretreatment. The improved method utilizes 2,4,6-tripyridyl-s-triazine that forms a blue colored complex specifically with iron in the presence of uric acid. The intensity of the color, measured at 590nm, is directly proportional to the uric acid concentration in the serum. The optimized formulation substantially reduces interference by substances in the raw samples.
KEY FEATURES Sensitive and accurate. Use 5 μL samples. Linear detection range 0.22-30mg/dL (13-2380μM) uric acid in 96-well plate assay. Simple and high-throughput. The procedure involves addition of a single working reagent and incubation for 30 min. Can be readily automated as a high-throughput assay in 96-well plates for thousands of samples per day. Improved reagent stability and versatility. The optimized formulation has greatly enhanced reagent and signal stability. Cuvet or 96-well plate assay. Low interference in biological samples. No pretreatments are needed. Assays can be directly performed on serum samples.
APPLICATIONS Direct Assays: uric acid in serum, plasma, urine and other biological samples. Drug Discovery/Pharmacology: effects of drugs on uric acid metabolism.
STORAGE CONDITIONS The kit is shipped at room temperature. Store reagents at 4 °C, standard and blank control at -20 °C. Shelf life of at least 6 months.
其他 :编号：DIUA-048，DIUA-250
测试：48T,250T